ABSTRACT

Objective: This purpose of this study was to investigate the effects of a multimodal interventional program(MIP) that combined physical activity and emotional activities centering on cognitive activities on cognitive function, instrumental activities of daily living(IADL) in patients with mild Alzheimer's Disease. Methods: A total of 59 patients with mild Alzheimer's disease were randomly assigned to a study group of 39 patients and a control group of 20 patients. For the experimental group, the multimodal intervention program and the control group were applied for the non-intervention. MIP was conducted twice a week for 8 weeks and for 110 minutes per session. In order to evaluate the cognitive function of the subjects, MMSE-DS, COSAS were used, and K-IADL was used to measure IADL. Results: Among the 59 patients with mild Alzheimer's disease who were taking medication, the group with MIP showed a statistically significant improvement in cognitive function and instrumental activities of daily living compared with the group without non-intervention(p<.01). Conclusion: The multimodal intervention program is the effective intervention program for the maintenance and improvement of cognitive function and IADL in patient with mild Alzheimer's disease.